Adaptogens in Medical Herbalism by Donald R. Yance CN MH RH(AHG)

Author:Donald R. Yance, CN, MH, RH(AHG)
Language: eng
Format: mobi, epub
Tags: Health/Herbal Medicine
Publisher: Inner Traditions / Bear & Company
Published: 2001-12-31T22:00:00+00:00

Anticarcinogenic: inhibits NF-κB; up-regulates cancer-suppressor genes; suppresses tumor initiation and growth; inhibits genetic mutations; triggers Fas-mediated apoptosis; activates caspase 3; inhibits VEGF and protein kinase C; inhibits epidermal growth factor receptor (EGFR); inhibits topoisomerase 1; decreases the activity of ornithine decarboxylase; inactivates matrix metalloproteinases (MMPs) 2 and 9; reduces the formation of N-nitrosodimethylamine (NDMA); reduces viability in Ehrlich ascites tumor cells; inhibits multidrug resistance; blocks tumor formation (bladder, prostate, colon, breast, ovaries, etc.); several human and animal studies have demonstrated significant cancer-preventive effects as well as the ability to suppress and slow the growth of several forms of cancers including prostate, breast, ovarian, cervical, endometrial, colon, gastric, bladder, pancreatic, liver, bile duct, head and neck, brain, skin, kidney, lymphoma, and chronic lymphocytic leukemia.

Protects skin from UV radiation damage

Redox/antioxidant: enhances a multitude of cellular defense pathways

Prevents and repairs DNA damage

Modulates reproductive hormone (androgen and estrogen) receptor activity, suppressing hormone-related cancers including breast and prostate; inhibits aromatase activity

Protects against lipid peroxidation

Promotes hepatic detoxification pathways

Anti-inflammatory

Protects against the progression of atrophic gastritis

Enhances fat metabolism: increases betaoxidation; has a thermogenic (antiobesity) effect; reduces serum lipids and lipoproteins

Antidiabetic/insulintrophic: improves several parameters of metabolic syndrome

Promotes cardiovascular health: lowers cholesterol, prevents atherosclerosis, and regulates blood pressure (there is an inverse association between green tea consumption and coronary atherosclerosis); prevents cardiac toxicity in doxorubicin chemotherapy

Decreases muscle necrosis (anticatabolic)

Neuroprotective

Increases life span

Antiviral (e.g., HPV, HIV, HSV-2, EBV, adenovirus)

Antibacterial: effective against staphylococcal enterotoxin B (SEB) and staphylococcal superantigens (SAgs) in atopic dermatitis; enhances beta-lactams in MR staph, H. pylori, and E. coli in the bladder and E. coli, Streptococcus salivarius, and Streptococcus mutans in dental caries

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